Bobin Chen Selected Research

Gelox

6/2022

Icaritin inhibits PLK1 to activate DNA damage response in NK/T cell lymphoma and increases sensitivity to GELOX regime.

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Bobin Chen Research Topics

Disease

15	Lymphoma (Lymphomas) 08/2022 - 08/2017
6	Neoplasms (Cancer) 01/2020 - 01/2009
3	T-Cell Lymphoma (Lymphoma, T Cell) 06/2022 - 05/2009
3	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2021 - 03/2014
2	Extranodal NK-T-Cell Lymphoma 01/2017 - 02/2015
2	Leukemia 09/2009 - 04/2009
1	Uveitis 07/2022
1	Autoimmune Diseases (Autoimmune Disease) 07/2022
1	Retinal Vasculitis 01/2022
1	Atrophy 01/2022
1	Epiretinal Membrane (Epiretinal Membranes) 01/2022
1	Fibrosis (Cirrhosis) 01/2022
1	Macular Edema 01/2022
1	Papilledema 01/2022
1	Intraocular Lymphoma 04/2021
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2017
1	Polyneuropathies (Polyneuropathy) 01/2017
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 02/2016
1	Pancytopenia 01/2012
1	Hypoalbuminemia 01/2012
1	Coma (Comas) 07/2010
1	Wounds and Injuries (Trauma) 07/2010
1	Hypertension (High Blood Pressure) 07/2010
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 07/2010
1	Acute Kidney Injury (Acute Renal Failure) 07/2010
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/2009
1	Retinoblastoma (Glioblastoma, Retinal) 02/2009
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 02/2009
1	Lung Neoplasms (Lung Cancer) 02/2009
1	Breast Neoplasms (Breast Cancer) 01/2009
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2007

Drug/Important Bio-Agent (IBA)

5	Methotrexate (Mexate)FDA LinkGeneric 06/2022 - 08/2017
2	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 06/2022 - 08/2017
2	icaritinIBA 06/2022 - 02/2015
2	Interleukin-10 (Interleukin 10)IBA 04/2021 - 01/2020
2	Rituximab (Mabthera)FDA Link 01/2021 - 03/2014
2	ResveratrolIBA 06/2020 - 01/2017
1	Biomarkers (Surrogate Marker)IBA 07/2022
1	B-Cell Activating FactorIBA 07/2022
1	LigandsIBA 07/2022
1	GeloxIBA 06/2022
1	Retinaldehyde (Retinal)IBA 01/2022
1	Myeloid Differentiation Factor 88IBA 04/2021
1	Proline (L-Proline)FDA Link 04/2021
1	Leucine (L-Leucine)FDA Link 04/2021
1	InterleukinsIBA 04/2021
1	Interleukin-6 (Interleukin 6)IBA 04/2021
1	Polo-Like Kinase 1IBA 06/2020
1	CytokinesIBA 01/2020
1	EstersIBA 01/2018
1	N- (2- amino- 5- fluorobenzyl)- 4- (N- (pyridine- 3- acrylyl)aminomethyl)benzamideIBA 01/2018
1	Histone Deacetylase InhibitorsIBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2017
1	Methylprednisolone FDA LinkGeneric 01/2017
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2017
1	Anticarcinogenic AgentsIBA 01/2017
1	AntioxidantsIBA 01/2017
1	Large Neutral Amino Acid-Transporter 1IBA 02/2016
1	epimedii flavoneIBA 02/2015
1	Alkaline PhosphataseIBA 01/2012
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2012
1	Mannitol (Osmitrol)FDA LinkGeneric 07/2010
1	Furosemide (Lasix)FDA LinkGeneric 07/2010
1	Torsemide (Demadex)FDA LinkGeneric 07/2010
1	AntigensIBA 09/2009
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 05/2009
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2009
1	Biological ProductsIBA 05/2009
1	HLA-DR Antigens (HLA-DR)IBA 04/2009
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2009
1	Retinoblastoma ProteinIBA 02/2009
1	alvocidib (flavopiridol)IBA 02/2009
1	Messenger RNA (mRNA)IBA 01/2009
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2009
1	Docetaxel (Taxotere)FDA Link 02/2007
1	Pemetrexed (MTA)FDA Link 02/2007

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 08/2022 - 02/2007
1	Aftercare (After-Treatment) 01/2022
1	Vitrectomy 05/2020
1	Craniotomy 01/2020
1	Artificial Respiration (Mechanical Ventilation) 07/2010
1	Erythrocyte Transfusion 07/2010